We would like to invite you to attend the HDR Confirmation of Rickyle Balea, a Doctor of Philosophy candidate in the School of Science Technology and Engineering. If you are external to 世界杯预选赛竞猜 and wish to participate via Zoom, please contact ASURE@weatheredwatcher.com.
Rapid diagnostic tests for low-resource surveillance of Arboviruses in a multiplexed detection format
The prevalence of novel as well as re-emerging viruses continue to pose significant global health threats to society. Influences such as climate change, globalisation and increasing population densities continue to drastically fuel the emergence of pathogenic viruses. Arthropod vectored viruses are responsible for the overwhelming majority of all emerging and re-emerging virus outbreaks world-wide. Most Arboviruses are known to rapidly mutate, resulting in several strains and variants, which can often result in major obstacles in development of treatments and vaccines. The most favourable countermeasure therefore, is early detection and effective surveillance of emerging viruses. Current diagnostics involve techniques such as RT-PCR and serology for suitable detection and diagnostics for Arboviruses. Although sufficient, these conventional techniques do present several limitations with regards to rapid point-of-care (POC) aspects. Advancement in isothermal amplification techniques continues to revolutionise the field of pathology and is steadily becoming the more favourable approach in POC diagnostics. This PhD project will aim to investigate the use of recombinase aided amplification (RAA) coupled with lateral flow strip detection (LFD) as a means for specific and highly sensitive Arbovirus detection and surveillance.